Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237166 | 0.85 | GABRA1 (0.54) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL2705985 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL16966280 | 0.83 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL11786355 | 0.82 | HTT (0.44) | CYP3A4KMT2AMEN1HTTHDAC3 | |
| SCHEMBL4938884 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL14969275 | 0.81 | GABRA1 (0.44) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL3251271 | 0.81 | CYP3A4 (0.47) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| Benzene SCHEMBL27083018 | 0.81 | FOLH1 (0.55) | GABRA1GABRB2CYP3A4KDM4EHPGD | |
| SCHEMBL474921 | 0.81 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4KDM4EHSD17B10 | |
| SCHEMBL89060 | 0.81 | FOLH1 (0.55) | GABRA1GABRB2CYP3A4KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045571-A1 | Process for the production of phenyl substituted aldehydes and of phenyl substituted alcohols | BUSH BOAKE ALLEN Limited (GB) | 1982-02-10 | — | — | EP | claimed |
| US-20230076320-A1 | NORFENFLURAMINE TO TREAT DRAVET SYNDROME | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-03-09 | — | — | US | disclosed |
| US-20200297665-A1 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | ZOGENIX INTERNATIONAL LIMITED (GB) | 2020-09-24 | — | — | US | disclosed |
| EP-3518908-A2 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | Zogenix International Limited (GB) | 2019-08-07 | — | — | EP | disclosed |
| WO-2018060732-A2 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | ZOGENIX INTERNATIONAL LIMITED (GB) | 2018-04-05 | — | — | WO | disclosed |
| US-20180092864-A1 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | ZOGENIX INTERNATIONAL LIMITED (GB) | 2018-04-05 | — | — | US | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0850948-B1 | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-6048842-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0850948-A1 | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0424242-A2 | Process for preparing carboxylic acids by means of oxidation of corresponding aldehydes | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230076320-A1 | NORFENFLURAMINE TO TREAT DRAVET SYNDROME | TPH2, HTR5A, TPH1 | GABRA1 147/4885GABRB2 42/4885CYP3A4 505/4885 |
| US-20180092864-A1 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | PSEN2, EPM2A, TPH2 | GABRA1 114/4885GABRB2 41/4885CYP3A4 311/4885 |
| US-20200297665-A1 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS | PSEN2, EPM2A, TPH2 | GABRA1 114/4885GABRB2 41/4885CYP3A4 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.