Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695959 | 0.88 | LMNA (0.47) | LMNAHTTFNTAFNTBCNR1 | |
| SCHEMBL31496743 | 0.81 | HTT (0.54) | CHRM2LMNAHTTFNTAFNTB | |
| SCHEMBL2380021 | 0.80 | FNTA (0.52) | CHRM2LMNAHTTFNTAFNTB | |
| SCHEMBL11077147 | 0.79 | HTT (0.53) | CHRM2HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL6688452 | 0.77 | PARP1 (0.48) | PARP1MAPTKDM4EALDH1A1TP53 | |
| SCHEMBL2378330 | 0.76 | L3MBTL1 (0.55) | CHRM2LMNAHTTFNTAFNTB | |
| SCHEMBL6691901 | 0.74 | CCR2 (0.47) | LMNAPARP1MAPTTP53TSHR | |
| SCHEMBL6688446 | 0.73 | PARP1 (0.46) | HTTCNR1PARP1MAPTALDH1A1 | |
| SCHEMBL19457202 | 0.72 | HTT (0.66) | LMNAHTTKDM4EALDH1A1TSHR | |
| SCHEMBL2377252 | 0.72 | ALDH1A1 (0.55) | HTTKDM4EALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |