Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163627 | 0.85 | ALDH1A1 (0.34) | MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL23536632 | 0.82 | VNN1 (0.38) | L3MBTL1MEN1KMT2ACYP2D6VNN1 | |
| SCHEMBL6134036 | 0.80 | USP2 (0.43) | SMN1; SMN2 | |
| SCHEMBL1315531 | 0.77 | CYP2D6 (0.35) | MEN1KMT2ACYP2D6VNN1OPRM1 | |
| SCHEMBL5974563 | 0.75 | USP2 (0.34) | MEN1KMT2ACYP2D6VNN1CYP46A1 | |
| SCHEMBL27746269 | 0.73 | CYP46A1 (0.30) | CYP46A1 | |
| SCHEMBL18040925 | 0.73 | JAK2 (0.35) | MEN1KMT2ACYP2D6CYP46A1ALDH1A1 | |
| SCHEMBL6134891 | 0.73 | USP2 (0.46) | SMN1; SMN2CYP2D6ALDH1A1 | |
| SCHEMBL6134918 | 0.73 | CES2 (0.33) | — | |
| SCHEMBL4782236 | 0.72 | OPRM1 (0.49) | L3MBTL1MEN1KMT2ATDP1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113368-A1 | CYCLIC LIPOPEPTIDES | ASTELLAS PHARMA INC. (JP) | 2004-12-29 | — | — | WO | disclosed |