SCHEMBL669785

SCHEMBL669785

COc1ccc(-c2nc(N)nc(N)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.58
HPGD P15428 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
NPC1 O15118 4/20 0.56
CYP1A2 P05177 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
RAB9A P51151 2/20 0.55
CHRNA7 P36544 1/20 0.55
ADORA1 P30542 2/20 0.54
IKBKB O14920 1/20 0.54
BRAF P15056 1/20 0.54
KDM4E B2RXH2 3/20 0.54
CYP1A1 P04798 1/20 0.54
CYP1B1 Q16678 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6978351 0.98 DYRK1A (0.56) DYRK1AHPGDSMN1; SMN2MAPTMEN1
SCHEMBL3418789 0.96 DYRK1A (0.58) DYRK1AHPGDSMN1; SMN2MAPTMEN1
SCHEMBL10822485 0.85 NPC1 (0.58) DYRK1AHPGDSMN1; SMN2MAPTMEN1
SCHEMBL6316030 0.84 HSP90AA1 (0.66) DYRK1AHPGDSMN1; SMN2MAPTMEN1
SCHEMBL338452 0.84 CLK4 (0.64) SMN1; SMN2MAPTMEN1KMT2ANPC1
SCHEMBL15896952 0.82 CLK4 (0.61) SMN1; SMN2MAPTMEN1KMT2ANPC1
SCHEMBL2876553 0.82 CLK4 (0.61) SMN1; SMN2MAPTMEN1KMT2ANPC1
SCHEMBL2178398 0.82 DYRK1A (0.61) DYRK1AHPGDSMN1; SMN2MAPTMEN1
SCHEMBL28880529 0.82 RAB9A (0.76) HPGDSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL14432249 0.81 KMT2A (0.53) DYRK1ASMN1; SMN2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN claimed
WO-2024046225-A1 ESTER TYPE PHOTOSENSITIVE POLYIMIDE COMPOSITE MATERIAL, PREPARATION METHOD AND SEMICONDUCTOR APPARATUS 深圳先进电子材料国际创新研究院 2024-03-07 WO claimed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-115509088-A Ester type photosensitive polyimide composite material, preparation method and semiconductor device 深圳先进电子材料国际创新研究院 2022-12-23 CN claimed
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN disclosed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN disclosed
US-11844802-B2 Compounds and compositions for ossification and methods related thereto EMORY UNIVERSITY (US) 2023-12-19 US disclosed
US-20230044670-A1 Compounds and Compositions for Ossification and Methods Related Thereto UNIV EMORY (US) 2023-02-09 US disclosed
US-11566168-B1 Biocide blend for treating wellbores HALLIBURTON ENERGY SERVICES, INC. (US) 2023-01-31 US disclosed
WO-2023287453-A1 BIOCIDE BLEND FOR TREATING WELLBORES HALLIBURTON ENERGY SERVICES, INC. (US) 2023-01-19 WO disclosed
CN-115509088-A Ester type photosensitive polyimide composite material, preparation method and semiconductor device 深圳先进电子材料国际创新研究院 2022-12-23 CN disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed
US-7038046-B2 Triazine derivatives and their use as sunscreens CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-05-02 US disclosed
US-20040242579-A1 Triazine derivatives and their use as sunscreens CIBA SPECIALTY CHEMICALS CORP. 2004-12-02 US disclosed
EP-1423371-A1 TRIAZINE DERIVATIVES AND THEIR USE AS SUNSCREENS Ciba SC Holding AG (CH) 2004-06-02 EP disclosed
WO-2003016289-A1 TRIAZINE DERIVATIVES AND THEIR USE AS SUNSCREENS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-27 WO disclosed
EP-0563386-A1 ANTICANCER COMPOSITION AND COMPOUND NIPPON SHINYAKU COMPANY, LIMITED (JP) 1993-10-06 EP disclosed
US-4873242-A NOOTROPIC AGENTS NIPPON SHINYAKU CO., LTD. (JP) 1989-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11566168-B1 Biocide blend for treating wellbores KAT2B, WEE2, OTUB1 DYRK1A 2456/4885HPGD 2390/4885SMN1; SMN2 2574/4885
US-20230044670-A1 Compounds and Compositions for Ossification and Methods Related Thereto BMP2, SOST, BMP4 DYRK1A 2341/4885HPGD 926/4885SMN1; SMN2 2252/4885
US-20040242579-A1 Triazine derivatives and their use as sunscreens CBR1, CBR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 DYRK1A 3219/4885HPGD 1162/4885SMN1; SMN2 3595/4885
US-11844802-B2 Compounds and compositions for ossification and methods related thereto BMP2, SOST, BMP4 DYRK1A 2341/4885HPGD 926/4885SMN1; SMN2 2252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.