SCHEMBL6698243

SCHEMBL6698243

C#Cc1cc(C#C)cc(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
GFER P55789 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.37
EPHX2 P34913 2/20 0.36
PGR P06401 1/20 0.36
MAPT P10636 2/20 0.35
USP2 O75604 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 1/20 0.35
NPC1 O15118 1/20 0.34
CNR2 P34972 4/20 0.31
MDH2 P40926 1/20 0.31
HIF1A Q16665 1/20 0.31
STS P08842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6392406 0.89 PGR (0.47) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL6764286 0.86 LMNA (0.40) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL4054713 0.85 PGR (0.39) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2763378 0.84 PGR (0.55) LMNAALDH1A1MEN1KMT2APGR
SCHEMBL2189703 0.84 PGR (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2190764 0.84 PGR (0.35) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL27798260 0.83 ALDH1A1 (0.33) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2763070 0.80 PGR (0.44) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2189735 0.80 PGR (0.41) LMNAALDH1A1PGRGRIN2DGRIN3B
SCHEMBL419847 0.80 LMNA (0.57) LMNAALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed
US-20040127715-A1 Adamantane compounds and insulating film forming coating solutions SUMITOMO CHEMICAL COMPANY, LIMITED 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127715-A1 Adamantane compounds and insulating film forming coating solutions CHRNA1, ANO1, CHRNA2 LMNA 1204/4885ALDH1A1 335/4885MEN1 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.