Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733150 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNANPSR1CYP1A2 | |
| SCHEMBL1639080 | 0.77 | LMNA (0.43) | MAPTALDH1A1LMNAADRA2AKMT2A | |
| SCHEMBL9786136 | 0.77 | LMNA (0.43) | MAPTALDH1A1LMNAADRA2AKMT2A | |
| SCHEMBL13490418 | 0.76 | MAPT (0.41) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL8127951 | 0.76 | ADRB1 (0.45) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8133139 | 0.76 | ADRB1 (0.45) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| Oxalic Acid SCHEMBL522460 | 0.74 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27592214 | 0.74 | PARP1 (0.34) | — | |
| SCHEMBL9318307 | 0.72 | NQO2 (0.40) | MAPTALDH1A1CYP1A2KDM4ERAB9A | |
| SCHEMBL3387040 | 0.72 | MAPT (0.49) | MAPTALDH1A1LMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1594298-A | Pyridine ring containing oxazolidinone compounds and preparation process and application thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2005-03-16 | — | — | CN | claimed |
| CN-100545150-C | Contain pyridine ring De oxazolidone compounds, Preparation method and use | SHANGHAI INST MATERIA MEDICA (CN) | 2009-09-30 | — | — | CN | disclosed |
| CN-1594298-A | Pyridine ring containing oxazolidinone compounds and preparation process and application thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2005-03-16 | — | — | CN | disclosed |
| US-20040009988-A1 | Bioisosteric bensamide derivatives and their use as apob-100 secretion inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-01-15 | — | — | US | disclosed |
| EP-1289982-A1 | BIOISOSTERIC BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096327-A1 | BIOISOSTERIC BENZAMIDE DERIVATIVES AND THEIR USE AS APoB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009988-A1 | Bioisosteric bensamide derivatives and their use as apob-100 secretion inhibitors | APOB, APOL1, TTR | MAPT 1281/4885ALDH1A1 2752/4885LMNA 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.