Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814642 | 0.82 | LMNA (0.43) | LMNAALDH1A1 | |
| SCHEMBL2805436 | 0.82 | CCR2 (0.39) | LMNAALDH1A1HPGD | |
| SCHEMBL2353804 | 0.79 | PARP1 (0.40) | ALDH1A1 | |
| SCHEMBL5673745 | 0.78 | BRD4 (0.43) | ALDH1A1 | |
| Trichloroacetic Acid SCHEMBL27834532 | 0.76 | LMNA (0.39) | LMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27834531 | 0.75 | LMNA (0.38) | LMNAMAPT | |
| SCHEMBL9640312 | 0.75 | TSHR (0.34) | — | |
| SCHEMBL9640334 | 0.74 | CYP2D6 (0.35) | LMNAALDH1A1MAPT | |
| Bromide SCHEMBL9595302 | 0.74 | TSHR (0.33) | — | |
| Bromide SCHEMBL9595609 | 0.73 | CYP2D6 (0.35) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235084-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | ENERGY, UNITED STATES DEPARTMENT OF | 2004-11-25 | — | — | US | disclosed |
| US-6716596-B2 | biomimic cofactor; 3-substituted pyridium compounds; nicotinamides N-substituted with benzyl or polyoxyethylene glycol derivatives; bipyridyl rhodium hydride complex catalyst for reduction of the cofactor; polymer matrix; economical in large scale; biosensor or a chemical membrane bioreactor | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235084-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | NQO1, NADK, ME2 | KDM4E 3361/4885LMNA 3814/4885ALDH1A1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.