SCHEMBL6700097

SCHEMBL6700097

CC1N=C(c2ccc(C3=NC(C)C(=O)O3)cc2)OC1=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
USP1 O94782 2/20 0.30
WDR48 Q8TAF3 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3379728 0.90 USP1 (0.41) NPC1RAB9AUSP1WDR48
SCHEMBL6699829 0.84 NPC1 (0.40) NPC1RAB9AUSP1WDR48
SCHEMBL6697908 0.78 ALOX15 (0.38) NPC1RAB9AUSP1WDR48
SCHEMBL8129464 0.70 F2 (0.44)
SCHEMBL6695032 0.69 RAB9A (0.35) NPC1RAB9A
SCHEMBL6136318 0.69 SMN1; SMN2 (0.32)
SCHEMBL2876279 0.67
SCHEMBL22628222 0.66 MAOB (0.43) NPC1RAB9A
SCHEMBL9461927 0.66 USP1 (0.36) NPC1RAB9AUSP1WDR48
SCHEMBL8138450 0.66 USP1 (0.38) NPC1RAB9AUSP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040068059-A1 Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2004-04-08 US disclosed
EP-1354908-A1 ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2003-10-22 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
EP-0185493-B1 IMIDAZOLINONE-CONTAINING POLYMERS AND COPOLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-28 EP disclosed
US-5139885-A Aroamtic polester, halogenated diol, diglycidyl or dicarboxylic acid and a-di-heterocyclic compound; flexible heat stable POLYPLASTICS CO., LTD. (JP) 1992-08-18 US disclosed
US-5079284-A Halogenated nitrogen heterocycle as flame retardant POLYPLASTICS CO., LTD. (JP) 1992-01-07 US disclosed
US-4954541-A POLYESTER, HALOGENATED COMPOUND, HETEROCYCLIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1990-09-04 US disclosed
US-4785070-A THERMAL CYCLODEHYDRATION OF AN AZLACTONE OR 4,4-DISUBSTITUTED 2-OXAZOLIN-5-ONE AND DIAMINE; WATER SOLUBILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-15 US disclosed
US-4785046-A Poly(5-imidazolone) and process therefor W. R. GRACE & CO.-CONN. (US) 1988-11-15 US disclosed
US-4705824-A Poly(5-imidazolone) and process therefor W. R. GRACE & CO. (US) 1987-11-10 US disclosed
US-4684601-A UNSATURATED, HIGH MOLECULAR WEIGHT DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-08-04 US disclosed
US-4640887-A C,M UNSATURATED POLYESTERS WITH FREE CARBOXY GROUPS; PRINTING DURABLE PLATES WITH IMPROVED OLEOPHILICITY DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-02-03 US disclosed
EP-0185493-A2 Imidazolinone-containing polymers and copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-06-25 EP disclosed
US-4591545-A Photosensitive image-forming material having a layer of photosensitive polyester modified with chain extender DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-05-27 US disclosed
EP-0019061-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS TEIJIN LIMITED (JP) 1984-08-08 EP disclosed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US disclosed
US-4266040-A Polyazlactone-electron deficient ethylenically unsaturated resinous compositions and method for foaming same DESOTO, INC. (US) 1981-05-05 US disclosed
EP-0019061-A1 Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters TEIJIN LIMITED (JP) 1980-11-26 EP disclosed