Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700097 | 0.90 | MMP2 (0.32) | USP1WDR48NPC1RAB9A | |
| SCHEMBL6699829 | 0.87 | NPC1 (0.40) | USP1WDR48NPC1RAB9AMAPT | |
| SCHEMBL9055482 | 0.83 | MMP2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6697908 | 0.81 | ALOX15 (0.38) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8138450 | 0.77 | USP1 (0.38) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7895962 | 0.77 | USP1 (0.38) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3384117 | 0.76 | USP1 (0.40) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8026358 | 0.75 | USP1 (0.37) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4046759 | 0.73 | USP1 (0.38) | USP1WDR48SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4054286 | 0.73 | SMN1; SMN2 (0.44) | USP1WDR48SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676423-B2 | Structure and synthesis of highly fluorinated amino acid derivatives | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20200123099-A1 | Structure and Synthesis of Highly Fluorinated Amino Acid Derivatives | UNIV OKLAHOMA STATE (US) | 2020-04-23 | — | — | US | disclosed |
| WO-2018156500-A1 | STRUCTURE AND SYNTHESIS OF HIGHLY FLUORINATED AMINO ACID DERIVATIVES | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2018-08-30 | — | — | WO | disclosed |
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE | 2016-08-04 | — | — | US | disclosed |
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE | 2016-08-04 | — | — | US | disclosed |
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE | 2016-08-04 | — | — | US | disclosed |
| US-8552206-B2 | NF-κB inhibitors and uses thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2013-10-08 | — | — | US | disclosed |
| US-7858808-B2 | Multi-substituted imidazolines and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100204260-A1 | Multi-Substituted Imidazolines And Method Of Use Thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2010-08-12 | — | — | US | disclosed |
| US-7652056-B2 | Using 4-imidazoline carboxylic acid or ester; antiinflammatory agents; microbiocides; bactericides; antitumor agenst0 | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-01-26 | — | — | US | disclosed |
| WO-2003101954-A2 | NF-KB INHIBITORS AND USES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-12-11 | — | — | WO | disclosed |
| WO-2003101969-A1 | MULTI-SUBSTITUDED IMIDAZOLINES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-12-11 | — | — | WO | disclosed |
| EP-0977742-B1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND ALPHA, ALPHA-DISUBSTITUTED AMINO ACIDS | UNIV LELAND STANFORD JUNIOR (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6130337-A | ALKYLATING AN ALLYLIC ELECTROPHILE WITH A 5-OXAZOLONE IN PRESENCE OF A BASE | BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0977742-A1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND ALPHA, ALPHA-DISUBSTITUTED AMINO ACIDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998046578-A1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND α,α-DISUBSTITUTED AMINO ACIDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1998-10-22 | — | — | WO | disclosed |
| US-5541080-A | SOLVOLYSIS WITH METHANOL IN PRESENCE OF A LIPASE IN NON-POLAR SOLVENT FOLLOWED BY ENANTIOSELECTIVELY CLEAVING ESTER WITH A PROTEASE | WISCONSIN ALUMNI RESEARCH FDN. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5219731-A | Cleaving an oxazolone precursor with lipase | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-4339589-A | Preparation of 4-substituted oxazolidin-5-ones | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4264771-A | Alkylation of substituted oxazolinone-(5) compounds | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123099-A1 | Structure and Synthesis of Highly Fluorinated Amino Acid Derivatives | PFAS, BCAT2, SLC7A1 | USP1 1276/4885WDR48 3100/4885SMN1; SMN2 3762/4885 |
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | SCLY, SELENOI, BHMT | USP1 552/4885WDR48 3908/4885SMN1; SMN2 1572/4885 |
| US-10676423-B2 | Structure and synthesis of highly fluorinated amino acid derivatives | PFAS, BCAT2, SLC7A1 | USP1 1276/4885WDR48 3100/4885SMN1; SMN2 3762/4885 |
| US-20100204260-A1 | Multi-Substituted Imidazolines And Method Of Use Thereof | NFKBIA, IKBKB, CHUK | USP1 2542/4885WDR48 3041/4885SMN1; SMN2 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.