SCHEMBL6697908

SCHEMBL6697908

CC1N=C(c2ccccc2-c2ccccc2C2=NC(C)C(=O)O2)OC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
POLB P06746 2/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
MAPK1 P28482 2/20 0.34
RAB9A P51151 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
S100A4 P26447 2/20 0.34
CES2 O00748 1/20 0.34
APAF1 O14727 1/20 0.34
TERT O14746 1/20 0.34
PLIN1 O60240 1/20 0.34
TDP2 O95551 1/20 0.34
S1PR4 O95977 1/20 0.34
LMNA P02545 1/20 0.34
PLA2G1B P04054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8129464 0.83 F2 (0.44) TDP1MEN1KMT2AKDM4EMAPT
SCHEMBL3379728 0.81 USP1 (0.41) MEN1KMT2ANPC1MAPTMAPK1
SCHEMBL6700097 0.78 MMP2 (0.32) NPC1RAB9AUSP1WDR48
SCHEMBL6699829 0.76 NPC1 (0.40) ALOX15MEN1KMT2AKDM4ENPC1
SCHEMBL9055482 0.72 MMP2 (0.41) ALOX15MEN1KMT2ANPC1MAPT
SCHEMBL6698793 0.70 NOS3 (0.42) ALOX15TDP1MEN1KMT2APOLB
SCHEMBL4023013 0.66 MMP9 (0.37) MEN1KMT2ALMNA
SCHEMBL2876279 0.63
SCHEMBL12646072 0.60 MEN1 (0.52) ALOX15MEN1KMT2APOLBKDM4E
SCHEMBL6702045 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040068059-A1 Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2004-04-08 US disclosed
EP-1354908-A1 ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2003-10-22 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
US-5139885-A Aroamtic polester, halogenated diol, diglycidyl or dicarboxylic acid and a-di-heterocyclic compound; flexible heat stable POLYPLASTICS CO., LTD. (JP) 1992-08-18 US disclosed
US-5079284-A Halogenated nitrogen heterocycle as flame retardant POLYPLASTICS CO., LTD. (JP) 1992-01-07 US disclosed
US-4954541-A POLYESTER, HALOGENATED COMPOUND, HETEROCYCLIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1990-09-04 US disclosed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US disclosed