Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946125 | 0.85 | ALDH1A1 (0.56) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL31294203 | 0.85 | ALDH1A1 (0.56) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL6946124 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7346902 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL27691294 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL27780855 | 0.80 | SYK (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL7212486 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL27815110 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL14943541 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7208161 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | VCAM1, LTB4R, ITGB4 | ALDH1A1 710/4885SLC1A3 3032/4885SLC1A2 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.