Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746322 | 0.73 | ELANE (0.41) | ACHEMEN1KMT2A | |
| SCHEMBL5584056 | 0.68 | TYR (0.55) | TYRBCHEACHEMEN1KMT2A | |
| SCHEMBL5677734 | 0.67 | LMNA (0.51) | TYRKMT2A | |
| SCHEMBL50738 | 0.65 | TYR (0.54) | TYRBCHEACHEMEN1KMT2A | |
| SCHEMBL6707321 | 0.63 | ALDH1A1 (0.41) | TYRBCHEACHE | |
| SCHEMBL5058761 | 0.63 | TYR (0.36) | TYRBCHEACHEKMT2A | |
| SCHEMBL7449654 | 0.62 | CYP19A1 (0.44) | — | |
| SCHEMBL4625871 | 0.62 | TYR (0.38) | TYRBCHEACHE | |
| SCHEMBL5053957 | 0.61 | TYR (0.34) | TYRBCHEACHEKMT2A | |
| SCHEMBL8979244 | 0.60 | TRPA1 (0.57) | TYRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116685-A1 | Method for solution phase synthesis of oligonucleotides | PROLIGO LLC | 2004-06-17 | — | — | US | disclosed |
| US-6262251-B1 | PRODUCT ANCHORED SEQUENCIAL SYNTHESIS (PASS); AN ANCHOR GROUP ATTACHED TO THE 5' END OF THE GROWING OLIGONUCLEOTIDE PRODUCT ALLOWS THE COUPLED PRODUCT TO BE SEPARATED FROM UNREACTED STARTING MATERIALS | PROLIGO LLC | 2001-07-17 | — | — | US | disclosed |
| EP-0979233-A4 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | PROLIGO L L C (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0979233-A1 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | NeXstar Pharmaceuticals, Inc. (US) | 2000-02-16 | — | — | EP | disclosed |
| US-6001966-A | REACTING N-TERMINAL PROTECTED AMINO ACID WITH PEPTIDE STARTING MATERIAL FORMING A PEPTIDE PRODUCT, PARTITIONING FROM UNREACTED MATERIAL AND REAGENTS BASED ON PRESENCE OF N-TERMINAL BLOCKING/ANCHORING GROUP | PROLIGO LLC (US) | 1999-12-14 | — | — | US | disclosed |
| US-5874532-A | USING A N-TERMINAL PROTECTED AMINO ACID MONOMER | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1998047910-A1 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | PROLIGO LLC (US) | 1998-10-29 | — | — | WO | disclosed |