Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696875 | 0.85 | ALDH1A1 (0.40) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| SCHEMBL6708640 | 0.81 | S100B (0.49) | ALDH1A1GFERCYP3A4TDP1TSHR | |
| SCHEMBL1143293 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL1143292 | 0.72 | ALDH1A1 (0.54) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| SCHEMBL9856682 | 0.71 | TDP1 (0.52) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| SCHEMBL526297 | 0.71 | TDP1 (0.52) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| SCHEMBL11580018 | 0.68 | TDP1 (0.48) | ALDH1A1GFERL3MBTL1CYP3A4TDP1 | |
| SCHEMBL6696798 | 0.68 | S100B (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6882632 | 0.67 | CYP2D6 (0.50) | ALDH1A1L3MBTL1CYP3A4RECQLSLC6A3 | |
| SCHEMBL11629765 | 0.67 | GAA (0.42) | ALDH1A1L3MBTL1TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506549-B1 | Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition | OREAL (FR) | 1995-10-18 | — | — | EP | claimed |
| EP-0446132-B1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | claimed |
| US-20040158941-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-19 | — | — | US | disclosed |
| US-20040158938-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY | 2004-08-19 | — | — | US | disclosed |
| US-6695888-B2 | COMPLEX TRANSITION METAL HAIR DYE | UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. | 2004-02-24 | — | — | US | disclosed |
| US-20040019980-A1 | One step hair coloring compositions using salts | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030113286-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | US | disclosed |
| US-20030110579-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | US | disclosed |
| US-20030066140-A1 | Transition metal complexes as dye forming catalysts in hair coloring compositions | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-04-10 | — | — | US | disclosed |
| US-5207798-A | Hair dyes | L'OREAL (FR) | 1993-05-04 | — | — | US | disclosed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | disclosed |
| US-4566875-A | HAIR DYES | L'OREAL (FR) | 1986-01-28 | — | — | US | disclosed |
| US-4425132-A | HAIR DYES, APPLYING WITHOUT RINSING | L'OREAL (FR) | 1984-01-10 | — | — | US | disclosed |
| US-4289495-A | HAIR DYES, STORAGE STABILITY | L'OREAL (FR) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110579-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | ALDH1A1 209/4885GFER 2933/4885L3MBTL1 3750/4885 |
| US-20040158941-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | ALDH1A1 1162/4885GFER 2795/4885L3MBTL1 4256/4885 |
| US-20040158938-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | ALDH1A1 209/4885GFER 2933/4885L3MBTL1 3750/4885 |
| US-20030113286-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | ALDH1A1 1162/4885GFER 2795/4885L3MBTL1 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.