Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274052 | 0.90 | KMT2A (0.63) | HTR6CYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL16027030 | 0.82 | HTR6 (0.66) | HTR6CYP19A1ALDH1A1HTTKDM4E | |
| SCHEMBL7753094 | 0.78 | HTR6 (0.69) | HTR6CYP19A1ALDH1A1KMT2AHTT | |
| Propionamide SCHEMBL9805665 | 0.78 | ICMT (0.48) | HTR6ALDH1A1SMN1; SMN2HTTCHRNB2 | |
| SCHEMBL4263977 | 0.78 | CYP2A6 (0.63) | HTR6ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10244867 | 0.77 | CYP19A1 (0.50) | CYP19A1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8986547 | 0.77 | HTR6 (0.67) | HTR6CYP19A1KMT2AYES1KDR | |
| SCHEMBL10465308 | 0.76 | CACNB4 (0.42) | HTR6CYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL7698481 | 0.76 | LMNA (0.77) | HTR6CYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL5462258 | 0.75 | ALDH1A1 (0.63) | HTR6ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
| EP-1322638-A1 | ANTIFUNGAL AND/OR ANTIPARASITIC PHARMACEUTICAL COMPOSITION AND NOVEL INDOLE DERIVATIVES AS ACTIVE PRINCIPLE OF SUCH A COMPOSITION | Yang Ji Chemical Company Ltd. (KR) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024685-A1 | INDOLE DERIVATIVES AND THEIR USE AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | YANG JI CHEMICAL COMPANY LTD. (KR) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | HTR6 265/4885CYP19A1 1538/4885ALDH1A1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.