Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710117 | 0.90 | GRM5 (0.39) | ALDH1A1KMT2AGRM5PYGLGRM4 | |
| SCHEMBL6713856 | 0.89 | PLCG2 (0.38) | ALDH1A1KMT2AGRM5PYGLGRM4 | |
| SCHEMBL6708060 | 0.88 | KMT2A (0.39) | ALDH1A1KMT2APYGLPLCG2PTK2B | |
| SCHEMBL6707938 | 0.87 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL6919649 | 0.86 | HDAC1 (0.37) | KMT2AGRM5PYGLGRM4PLCG2 | |
| SCHEMBL6714268 | 0.85 | LMNA (0.39) | HPGDALDH1A1MEN1KMT2APYGL | |
| SCHEMBL6711579 | 0.84 | CHRM1 (0.41) | SMN1; SMN2PYGLPLCG2PTK2B | |
| SCHEMBL6712466 | 0.83 | GPR35 (0.39) | USP2HPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6713534 | 0.83 | ALDH1A1 (0.40) | HPGDSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6713400 | 0.83 | TP53 (0.35) | HPGDMEN1KMT2APYGLPLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | USP2 842/4885HPGD 1253/4885SMN1; SMN2 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.