Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713856 | 0.97 | PLCG2 (0.38) | GRM5GRM4KMT2APLCG2PYGL | |
| SCHEMBL6708060 | 0.96 | KMT2A (0.39) | KMT2APLCG2PYGLALDH1A1PTK2B | |
| SCHEMBL6919649 | 0.95 | HDAC1 (0.37) | GRM5GRM4KMT2APLCG2GPR35 | |
| SCHEMBL6710224 | 0.90 | GPR35 (0.46) | GPR35RXFP2RXFP1KDM4EALDH1A1 | |
| SCHEMBL6707937 | 0.90 | USP2 (0.38) | GRM5GRM4KMT2APLCG2RXFP1 | |
| SCHEMBL6707932 | 0.89 | GPR35 (0.44) | GPR35RXFP1KDM4EALDH1A1 | |
| SCHEMBL6707660 | 0.89 | PLCG2 (0.37) | KMT2APLCG2SERPINE1PYGLPTK2B | |
| SCHEMBL6711709 | 0.88 | ROCK2 (0.36) | PLCG2PYGLPTK2BNHERF1 | |
| SCHEMBL6711704 | 0.88 | ROCK2 (0.36) | PLCG2PYGLPTK2BNHERF1 | |
| SCHEMBL6711711 | 0.88 | ROCK2 (0.36) | PLCG2PYGLPTK2BNHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRM5 4139/4885GRM4 4668/4885KMT2A 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.