Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710154 | 0.92 | GRIK1 (0.40) | GRIK1HIF1AMAP2K1ABL1HDAC1 | |
| SCHEMBL6708767 | 0.87 | HIF1A (0.35) | HIF1AMAP2K1HDAC1TMPRSS4CA12 | |
| SCHEMBL6711456 | 0.85 | HIF1A (0.46) | GRIK1HIF1AHDAC1KDM4EMEN1 | |
| SCHEMBL6710398 | 0.81 | LMNA (0.37) | GRIK1HIF1AMEN1ALDH1A1TP53 | |
| SCHEMBL6709033 | 0.79 | HIF1A (0.49) | GRIK1HIF1AALDH1A1KMT2AF11 | |
| SCHEMBL6709153 | 0.78 | EPHX2 (0.43) | GRIK1HIF1ACA12CA9KDM4E | |
| SCHEMBL6711801 | 0.78 | HIF1A (0.43) | GRIK1HIF1ACA12CA9KDM4E | |
| SCHEMBL6833746 | 0.78 | KCNK2 (0.39) | HIF1AMAP2K1S1PR1S1PR3KDM4E | |
| SCHEMBL6833974 | 0.78 | TAS2R14 (0.42) | GRIK1HIF1AMAP2K1CA12CA9 | |
| SCHEMBL6753986 | 0.77 | RORC (0.32) | MAP2K1S1PR1S1PR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885HIF1A 296/4885MAP2K1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.