Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713471 | 0.89 | RXFP1 (0.33) | MAPTABL1 | |
| SCHEMBL6710097 | 0.89 | HIF1A (0.34) | MAPT | |
| SCHEMBL6709838 | 0.87 | KDM4E (0.38) | ROCK2 | |
| SCHEMBL6707679 | 0.86 | SCN9A (0.33) | SCN9AMAPTMAP2K1ALKABL1 | |
| SCHEMBL6710200 | 0.85 | ALK (0.38) | ROCK2MAPTMAP2K1ALKTRPA1 | |
| SCHEMBL6710191 | 0.85 | ALK (0.38) | ROCK2MAPTMAP2K1ALKTRPA1 | |
| SCHEMBL6708677 | 0.84 | PKM (0.34) | ROCK2MAPTTRPA1 | |
| SCHEMBL6709087 | 0.84 | TRPA1 (0.42) | ROCK2MAPTTRPA1 | |
| SCHEMBL6833757 | 0.83 | ALB (0.35) | SCN9AMAPTMAP2K1TRPA1 | |
| SCHEMBL6710104 | 0.82 | TRPA1 (0.33) | ROCK2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SCN9A 3481/4885ROCK2 4868/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.