Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710533 | 0.90 | ALDH1A1 (0.34) | PKMLMNAPARP14MAPT | |
| SCHEMBL6709087 | 0.89 | TRPA1 (0.42) | ROCK2LMNATRPA1KDM1AMAPT | |
| SCHEMBL6707833 | 0.88 | RXFP1 (0.36) | THRBLMNAKDM1AMAPT | |
| SCHEMBL6711867 | 0.88 | HIF1A (0.37) | LMNA | |
| SCHEMBL6710104 | 0.87 | TRPA1 (0.33) | PKMROCK2THRBLMNATRPA1 | |
| SCHEMBL6713833 | 0.86 | CXCR1 (0.34) | PKMROCK2THRBLMNATRPA1 | |
| SCHEMBL6709838 | 0.86 | KDM4E (0.38) | ROCK2LMNA | |
| SCHEMBL6711902 | 0.85 | THRB (0.37) | PKMTHRBLMNATRPA1PDCD1 | |
| SCHEMBL6710210 | 0.85 | GSK3A (0.36) | THRBTRPA1CHRM3 | |
| SCHEMBL6713413 | 0.84 | PKM (0.33) | PKMROCK2THRBLMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PKM 3958/4885ROCK2 4868/4885THRB 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.