Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711946 | 0.92 | HPGD (0.39) | GRM4GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6708533 | 0.91 | USP2 (0.41) | PKMGRM4SMN1; SMN2RXFP1ROCK1 | |
| SCHEMBL6709950 | 0.89 | ROCK2 (0.39) | PKMGRM4SMN1; SMN2NPSR1ROCK1 | |
| SCHEMBL6713231 | 0.89 | GRM4 (0.39) | GRM4SMN1; SMN2GPR35HIF1ANPSR1 | |
| SCHEMBL6707879 | 0.88 | RXFP1 (0.37) | GRM4HIF1ANPSR1RXFP1ROCK1 | |
| SCHEMBL6708762 | 0.85 | PKM (0.37) | PKMGRM4SMN1; SMN2ROCK1ALDH1A1 | |
| SCHEMBL6708004 | 0.83 | RXFP1 (0.41) | GRM4SMN1; SMN2RXFP1ROCK1ALDH1A1 | |
| SCHEMBL6713418 | 0.83 | RXFP1 (0.36) | GRM4SMN1; SMN2GPR35HIF1ANPSR1 | |
| SCHEMBL6707636 | 0.82 | GPR35 (0.46) | SMN1; SMN2GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6711912 | 0.81 | EPHX1 (0.40) | GRM4RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PKM 3958/4885GRM4 4668/4885SMN1; SMN2 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.