Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713718 | 0.92 | HPGD (0.40) | GRIK1ROCK1ADORA2BADORA2AADORA1 | |
| SCHEMBL6711479 | 0.92 | RXFP1 (0.41) | PKMGRIK1ROCK1GRM4ALDH1A1 | |
| SCHEMBL6708925 | 0.89 | ADORA2B (0.36) | ROCK1ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6714295 | 0.89 | GRIK1 (0.41) | GRIK1ROCK1GRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6709869 | 0.88 | GRIK1 (0.38) | GRIK1ROCK1GRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6708928 | 0.85 | PKM (0.38) | PKMROCK1GRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6713186 | 0.84 | RXFP1 (0.42) | GRIK1ROCK1GRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6710171 | 0.83 | GRIK1 (0.38) | GRIK1ROCK1GRM4ALDH1A1MAPT | |
| SCHEMBL6713296 | 0.83 | PYGM (0.40) | GRIK1ROCK1GRM4 | |
| SCHEMBL6710606 | 0.83 | GRIK1 (0.40) | GRIK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PKM 3958/4885GRIK1 3885/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.