Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372735 | 0.84 | MAPKAPK2 (0.48) | MAPK8MAPK9MAPK10 | |
| SCHEMBL6775919 | 0.81 | DHFR (0.42) | NOTUMCYP1A2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL12761303 | 0.78 | NPC1 (0.61) | CYP1A2ALDH1A1CYP2C19SMN1; SMN2MAPK10 | |
| SCHEMBL12761250 | 0.78 | GP6 (0.37) | ALDH1A1HPGDESR1SMN1; SMN2TSHR | |
| SCHEMBL2028396 | 0.77 | ADH5 (0.32) | — | |
| SCHEMBL11937117 | 0.76 | CYP1A2 (0.47) | NOTUMCYP1A2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL6505461 | 0.76 | NR1H2 (0.41) | CYP1A2ALDH1A1NISCH | |
| SCHEMBL9941579 | 0.76 | ESR1 (0.56) | CYP1A2CYP11B1CYP11B2CYP2C9CYP2C19 | |
| SCHEMBL2217103 | 0.76 | TOP2A (0.51) | CYP1A2ALDH1A1NISCHCA12 | |
| SCHEMBL4950 | 0.76 | NR1H2 (0.43) | CYP1A2ALDH1A1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605247-A1 | ELASTOMERIC COMPOSITIONS FOR TYRES COMPRISING NNEEWW CROSS-LINKING FUNCTIONALISING AGENTS, ELASTOMERIC COMPOUNDS AND TYRES COMPRISING THEM | Pirelli Tyre S.p.A. (IT) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024084386-A9 | ELASTOMERIC COMPOSITIONS FOR TYRES COMPRISING NNEEWW CROSS-LINKING FUNCTIONALISING AGENTS, ELASTOMERIC COMPOUNDS AND TYRES COMPRISING THEM | PIRELLI TYRE S.P.A. (IT) | 2025-06-12 | — | — | WO | disclosed |
| WO-2024084386-A1 | ELASTOMERIC COMPOSITIONS FOR TYRES COMPRISING NNEEWW CROSS-LINKING FUNCTIONALISING AGENTS, ELASTOMERIC COMPOUNDS AND TYRES COMPRISING THEM | PIRELLI TYRE S.P.A. (IT) | 2024-04-25 | — | — | WO | disclosed |
| US-9918964-B2 | Reducing platelet activation, aggregation and platelet-stimulated thrombosis or blood coagulation by reducing mitochondrial respiration | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918964-B2 | Reducing platelet activation, aggregation and platelet-stimulated thrombosis or blood coagulation by reducing mitochondrial respiration | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918964-B2 | Reducing platelet activation, aggregation and platelet-stimulated thrombosis or blood coagulation by reducing mitochondrial respiration | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2012024495-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-23 | — | — | WO | disclosed |
| EP-1429763-A2 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-20030229120-A1 | Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer | NOVO NORDISK A/S (DK) | 2003-12-11 | — | — | US | disclosed |
| WO-2003027081-A2 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2003-04-03 | — | — | WO | disclosed |
| US-5656401-A | Electroluminescent device comprising oxadiazole compounds luminescent material, oxadiazole compounds for the device, and method of producing oxadiazole compounds | RICOH COMPANY, LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5610309-A | Electroluminescent device comprising oxadiazole compounds luminescent material, oxadiazole compounds for the device, and method of producing oxadiazole compounds | RICOH COMPANY, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5597925-A | CYCLIZATION | RICOH COMPANY, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| US-5420288-A | Electron transporting material, planar displays | RICOH COMPANY, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0332043-B1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-5216158-A | Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0332043-A1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | ABL1, ABL2, TST | NOTUM 2074/4885CYP1A2 351/4885CYP11B1 1884/4885 |
| US-20030229120-A1 | Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer | IAPP, IRS1, GPR119 | NOTUM 2460/4885CYP1A2 4860/4885CYP11B1 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.