Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445346 | 0.82 | UTS2R (0.42) | UTS2RALOX5ALDH1A1AOC3CYP1A2 | |
| SCHEMBL6445025 | 0.78 | KIF11 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19ACP3 | |
| SCHEMBL6447034 | 0.77 | AOC3 (0.42) | ALOX5ALDH1A1AOC3CYP1A2CYP2C9 | |
| SCHEMBL9734748 | 0.77 | UTS2R (0.44) | UTS2RALDH1A1AOC3CYP2C9CYP2C19 | |
| SCHEMBL1665813 | 0.77 | ALDH1A1 (0.55) | ALOX5ALDH1A1AOC3CYP1A2CYP2C9 | |
| SCHEMBL7302864 | 0.74 | ALDH1A1 (0.43) | ALOX5ALDH1A1AOC3CYP1A2CYP2C9 | |
| SCHEMBL6444521 | 0.74 | ALOX5 (0.41) | ALOX5ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18860719 | 0.73 | HTR1B (0.45) | UTS2RALDH1A1AOC3CYP1A2CYP2C9 | |
| SCHEMBL6243896 | 0.71 | ALDH1A1 (0.53) | ALOX5ALDH1A1AOC3CYP1A2CYP2C9 | |
| SCHEMBL25368292 | 0.70 | ALDH1A1 (0.44) | ALOX5ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |