SCHEMBL6709701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7142373	0.79	NPC1 (0.54)	ROCK1ROCK2PRKG1PRKACAGSK3A
	Hydrochloric Acid SCHEMBL11490909	0.79	CES2 (0.51)	ROCK1ROCK2PRKG1PRKACAGSK3A
	Bromide SCHEMBL6283052	0.78	NPC1 (0.53)	ROCK1ROCK2PRKG1PRKACAGSK3A
	Hydrochloric Acid SCHEMBL6708543	0.78	NPC1 (0.53)	ROCK1ROCK2PRKG1PRKACAGSK3A
	SCHEMBL6707539	0.76	ALDH1A1 (0.48)	ROCK1ROCK2PRKG1PRKACAGSK3A
	SCHEMBL1398796	0.75	CES2 (0.53)	KMT2AALDH1A1NPC1CES2CES1
	SCHEMBL6707538	0.73	LTA4H (0.47)	ROCK2CYP3A4KMT2AALDH1A1NPC1
	SCHEMBL7048516	0.73	CTSS (0.54)	MAPK1KMT2AALDH1A1NPC1CES2
	SCHEMBL4029309	0.72	CES2 (0.77)	MAPK1CYP2D6CYP3A4CYP2C9KMT2A
	SCHEMBL5216406	0.72	KMT2A (0.72)	CDK5CYP2D6KMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.