Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710115 | 0.94 | HDAC1 (0.35) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6710314 | 0.92 | HIF1A (0.41) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6708665 | 0.90 | IMPDH2 (0.35) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6708030 | 0.88 | ALDH1A1 (0.39) | HIF1ANPSR1RXFP1MEN1KMT2A | |
| SCHEMBL6709830 | 0.87 | BRD4 (0.39) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6707620 | 0.87 | AURKA (0.39) | AURKAAURKBHIF1AMEN1KMT2A | |
| SCHEMBL6709880 | 0.86 | TNIK (0.35) | HIF1ANPSR1RXFP1GPR35ROCK1 | |
| SCHEMBL6707823 | 0.85 | HIF1A (0.41) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6919439 | 0.85 | LMNA (0.38) | AURKAAURKBHIF1AMEN1KMT2A | |
| SCHEMBL6710273 | 0.85 | HIF1A (0.44) | HIF1ANPSR1RXFP1GPR35ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | AURKA 3954/4885AURKB 3449/4885PTPN2 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.