Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707880 | 0.92 | GAA (0.42) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL6710026 | 0.90 | ROCK2 (0.41) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL6713555 | 0.86 | RXFP1 (0.46) | MEN1KMT2ASMN1; SMN2GRM4RXFP1 | |
| SCHEMBL6710208 | 0.85 | RXFP1 (0.44) | MEN1KMT2ASMN1; SMN2HTTGRM4 | |
| SCHEMBL6708544 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2HTTUSP2 | |
| SCHEMBL6707706 | 0.85 | GRM4 (0.44) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL6709012 | 0.83 | ABL1 (0.45) | MEN1KMT2AMAPTRXFP1NPC1 | |
| SCHEMBL6711593 | 0.83 | RXFP1 (0.43) | SMN1; SMN2GRM4RXFP1ALDH1A1HPGD | |
| SCHEMBL6710298 | 0.83 | GRM4 (0.51) | MEN1KMT2AGRM4RXFP1NPC1 | |
| SCHEMBL6709891 | 0.83 | RXFP1 (0.46) | GRM4RXFP1ALDH1A1GRIK1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | MEN1 4100/4885KMT2A 3181/4885SMN1; SMN2 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.