Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | STK16 | O75716 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | STK11 | Q15831 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710122 | 0.90 | MEN1 (0.42) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6707880 | 0.89 | GAA (0.42) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6710082 | 0.87 | ROCK2 (0.37) | ROCK2SMN1; SMN2HSD17B10GRM4KLKB1 | |
| SCHEMBL6707687 | 0.86 | PYGM (0.39) | ROCK2MEN1KMT2AGRM4KLKB1 | |
| SCHEMBL6709892 | 0.85 | RAB9A (0.41) | ROCK2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6710030 | 0.85 | ROCK2 (0.45) | ROCK2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6707775 | 0.84 | ABL1 (0.42) | ROCK2MEN1KMT2AMAPT | |
| SCHEMBL6713177 | 0.84 | NAMPT (0.39) | ROCK2ALDH1A1SMN1; SMN2HPGDGRM4 | |
| SCHEMBL6713409 | 0.84 | TDP2 (0.42) | ROCK2BRPF1TNIKGRM4KLKB1 | |
| SCHEMBL6707688 | 0.83 | ADORA2B (0.38) | ROCK2ALDH1A1GRM4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK2 4868/4885ALDH1A1 123/4885MEN1 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.