Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708876 | 0.90 | MEN1 (0.45) | BRD4MAPTNPSR1MEN1KMT2A | |
| SCHEMBL6711640 | 0.90 | MEN1 (0.45) | BRD4MAPTNPSR1MEN1KMT2A | |
| SCHEMBL6709966 | 0.87 | PKLR (0.40) | BRD4PKLRMAPTNPSR1MEN1 | |
| SCHEMBL6710360 | 0.86 | TDP2 (0.41) | BRD4ROCK2 | |
| SCHEMBL6833349 | 0.85 | PKLR (0.45) | BRD4PKLRMAPTNPSR1MEN1 | |
| SCHEMBL6710142 | 0.81 | ROCK2 (0.41) | F2ROCK2 | |
| SCHEMBL6709982 | 0.81 | MAPT (0.38) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6711975 | 0.80 | TRPA1 (0.46) | MEN1KMT2AROCK2 | |
| SCHEMBL6710030 | 0.80 | ROCK2 (0.45) | MEN1KMT2AALDH1A1F2ROCK2 | |
| SCHEMBL6709087 | 0.78 | TRPA1 (0.42) | MAPTMEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | BRD4 1588/4885PKLR 4338/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.