Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6709530 | 0.99 | SIGMAR1 (0.46) | SIGMAR1CHRM2CHRM3DRD2DRD4 | |
| SCHEMBL6708297 | 0.90 | DRD2 (0.47) | DRD2DRD4CHRNB2CHRNA5CHRNA7 | |
| Hydrochloric Acid SCHEMBL6709532 | 0.89 | DRD2 (0.46) | DRD2DRD4CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL6707480 | 0.79 | DRD4 (0.46) | DRD2DRD4CHRNA4 | |
| SCHEMBL6713113 | 0.79 | PKM (0.40) | — | |
| SCHEMBL6707465 | 0.79 | ALDH1A1 (0.46) | DRD2DRD4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6709461 | 0.79 | DRD4 (0.46) | DRD2DRD4CHRNA4 | |
| SCHEMBL6545137 | 0.78 | SIGMAR1 (0.44) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6712863 | 0.78 | PKM (0.40) | — | |
| Hydrochloric Acid SCHEMBL6709587 | 0.78 | ALDH1A1 (0.45) | DRD2DRD4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | MERCK PATENT GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | CHRNA1, CHRNA2, CHRNA10 | SIGMAR1 390/4885CHRM2 15/4885CHRM3 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.