Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714061 | 0.89 | PLA2G4A (0.39) | LMNAMAPTTDP2KDM1AALDH1A1 | |
| SCHEMBL6707925 | 0.89 | RXFP1 (0.39) | LMNAMAPTHSP90AB1ABL1KDM1A | |
| SCHEMBL6713546 | 0.89 | HSP90AB1 (0.35) | LMNAMAPTHSP90AB1ABL1ALDH1A1 | |
| SCHEMBL6708819 | 0.86 | KDM1A (0.43) | LCKFYNKDM1A | |
| SCHEMBL6918878 | 0.85 | TDP2 (0.45) | MAPTTDP2KDM1AROCK2 | |
| SCHEMBL6708703 | 0.85 | ROCK2 (0.35) | LMNAMAPTTRPA1LCKFYN | |
| SCHEMBL6708917 | 0.85 | KDM1A (0.43) | LCKFYNKDM1A | |
| SCHEMBL6710317 | 0.83 | ROCK1 (0.45) | LMNATRPA1HSP90AB1LCKKDM1A | |
| SCHEMBL6710387 | 0.83 | TDP2 (0.43) | MAPTTDP2KDM1AALDH1A1 | |
| SCHEMBL6710082 | 0.83 | ROCK2 (0.37) | TRPA1LCKFYNF11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | LMNA 4062/4885MAPT 4754/4885TRPA1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.