Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 7/20 | 0.33 |
| ▸ | TDP2 | O95551 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714035 | 0.89 | ROCK2 (0.36) | ROCK2MAPTLMNAKDM1ATDP2 | |
| SCHEMBL6708021 | 0.89 | MAPT (0.41) | ROCK2TRPA1MAPTKDM1ATDP2 | |
| SCHEMBL6713492 | 0.88 | GPR35 (0.37) | MAPTLMNAALDH1A1TSHR | |
| SCHEMBL6710543 | 0.88 | RXFP1 (0.39) | ROCK2MAPTLMNAKDM1A | |
| SCHEMBL6917647 | 0.88 | KDM1A (0.32) | KDM1A | |
| SCHEMBL6714039 | 0.85 | KDM1A (0.44) | ROCK2KDM1AMAOARCOR1 | |
| SCHEMBL6711922 | 0.85 | LMNA (0.34) | ROCK2TRPA1MAPTLMNAKDM1A | |
| SCHEMBL6707785 | 0.85 | TDP2 (0.44) | ROCK2KDM1ATDP2MAOARCOR1 | |
| SCHEMBL6707752 | 0.84 | KDM1A (0.43) | ROCK2KDM1AMAOARCOR1 | |
| SCHEMBL6711975 | 0.83 | TRPA1 (0.46) | ROCK2TRPA1LMNAKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK2 4868/4885TRPA1 594/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.