Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 5/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 4/20 | 0.30 |
| ▸ | RARG | P13631 | 4/20 | 0.30 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037686 | 0.89 | RXRA (0.35) | PTGS1PTGS2RARACYP1A2CYP3A4 | |
| SCHEMBL6725577 | 0.87 | RARA (0.32) | PTGS1PTGS2RARACYP1A2CYP3A4 | |
| SCHEMBL6721524 | 0.79 | RXRA (0.35) | PTGS1PTGS2BACE1RARACYP1A2 | |
| SCHEMBL9036741 | 0.76 | RARA (0.34) | PTGS1PTGS2RARACYP1A2CYP3A4 | |
| SCHEMBL6725198 | 0.71 | BACE1 (0.31) | BACE1RARACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8346757 | 0.71 | HTT (0.33) | — | |
| SCHEMBL8133679 | 0.64 | MAPK1 (0.30) | — | |
| SCHEMBL6973404 | 0.64 | NOTUM (0.35) | PTGS2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6726207 | 0.64 | RXRA (0.35) | PTGS1PTGS2RARARARBRARG | |
| SCHEMBL7617142 | 0.64 | RXRA (0.39) | PTGS1PTGS2RARACYP3A4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677460-B1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-0712853-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-6136755-A | HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6103668-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6063936-A | CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0712853-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | XDH, SULT2A1, NAT1 | PTGS1 1669/4885PTGS2 2928/4885BACE1 2692/4885 |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | PTGS1 1669/4885PTGS2 2928/4885BACE1 2692/4885 |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | PTGS1 1669/4885PTGS2 2928/4885BACE1 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.