Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.41 |
| ▸ | MICA | Q29983 | 1/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506072 | 0.78 | TACR3 (0.51) | KMT2AKLRK1MICARAET1LLMNA | |
| SCHEMBL14831389 | 0.75 | PKM (0.48) | L3MBTL1RAB9AKLRK1MICARAET1L | |
| SCHEMBL16830012 | 0.73 | OPRK1 (0.44) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6825332 | 0.72 | SIGMAR1 (0.49) | SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL6715725 | 0.72 | MEN1 (0.54) | MEN1KMT2AS1PR4S1PR3KDM4E | |
| SCHEMBL28394955 | 0.72 | CHRNB2 (0.44) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17664138 | 0.71 | ALDH1A1 (0.56) | NPC1RAB9AS1PR4S1PR3LMNA | |
| SCHEMBL6716797 | 0.71 | HDAC1 (0.39) | HDAC1SLC6A2SLC6A4L3MBTL1NPC1 | |
| SCHEMBL24339824 | 0.71 | MLYCD (0.56) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4205971 | 0.71 | HPGD (0.55) | NPC1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | SLC1A2, SLC1A1, SLC7A11 | HDAC1 2586/4885SLC6A2 22/4885SLC6A4 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.