SCHEMBL6728060

SCHEMBL6728060

CCS(CC)(CC(=O)C(C)(C)C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.39
FAAH O00519 3/20 0.31
CES2 O00748 2/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6722981 0.85 FAAH (0.40) HSD11B1FAAHCES2CES1
SCHEMBL6728494 0.82 CA2 (0.33) HSD11B1
SCHEMBL6550547 0.81 ALDH1A1 (0.30)
SCHEMBL6734266 0.81 CA2 (0.34) HSD11B1
SCHEMBL6550659 0.80 HSD11B1 (0.37) HSD11B1
SCHEMBL6736327 0.80 HSD11B1 (0.40) HSD11B1
SCHEMBL5404639 0.78 CA1 (0.30)
SCHEMBL7160640 0.77 HSD11B1 (0.38) HSD11B1
SCHEMBL6550463 0.77 CXCR2 (0.30)
SCHEMBL6549785 0.77 FFAR3 (0.31) FAAHCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040224251-A1 Positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-11 US disclosed