Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724485 | 0.84 | GPR139 (0.34) | GPR139KDM4EALDH1A1TDP1 | |
| SCHEMBL7014884 | 0.81 | GPR139 (0.34) | GPR139KDM4EALDH1A1 | |
| SCHEMBL6724664 | 0.81 | RXFP1 (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL6730520 | 0.81 | S1PR3 (0.36) | DHODH | |
| SCHEMBL6729658 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL6729888 | 0.78 | ACLY (0.32) | GPR139ALDH1A1 | |
| SCHEMBL6724492 | 0.78 | GPR139 (0.35) | GPR139 | |
| SCHEMBL6729050 | 0.76 | PGR (0.37) | GPR139DHODH | |
| SCHEMBL6735913 | 0.75 | BCAT2 (0.33) | GPR139DHODH | |
| SCHEMBL6724560 | 0.74 | PPOX (0.35) | GPR139KDM4EALDH1A1TDP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1333031-A1 | BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | WEE1, WEE2, BAK1 | GPR139 1431/4885KDM4E 1331/4885ALDH1A1 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.