SCHEMBL673309

SCHEMBL673309

CC(C)(c1cc(Cl)cc(Cl)c1)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
CNR1 P21554 5/20 0.48
CNR2 P34972 5/20 0.48
CYP3A4 P08684 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
HSD17B10 Q99714 2/20 0.40
ALOX12 P18054 1/20 0.40
CASP1 P29466 1/20 0.40
RECQL P46063 1/20 0.40
HIF1A Q16665 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TP53 P04637 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 2/20 0.33
AR P10275 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803437 0.81 TSHR (0.50) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL9403849 0.79 TSHR (0.47) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL9602565 0.79 TSHR (0.47) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL25134468 0.77 TSHR (0.44) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL2646961 0.77 TSHR (0.44) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL4495782 0.77 TSHR (0.44) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL15449818 0.77 TSHR (0.44) TSHRCNR1CNR2CYP3A4ALDH1A1
1,3,5-Trichlorobenzene SCHEMBL23244766 0.76 TSHR (0.61) TSHRCNR1CNR2CYP3A4ALDH1A1
SCHEMBL10183607 0.75 GABRA1 (0.52) TSHRCNR1CNR2ALDH1A1HPGD
SCHEMBL5852530 0.75 TSHR (0.42) TSHRCNR1CNR2CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6018055-A MADE FROM A 1,3,5,7-TETRAOXO,2,6-DISUBSTITUTED,4,8-DI(NITRO OR HALO)BENZO(1,2-C:4,5-C')DIPYRROLE OF GIVEN FORMULA AND AN OPTIONALLY SUBSTITUTED AROMATIC RING, ALIPHATIC RING, OR HETEROAROMATIC RING DIOL; HEAT RESISTANT ENGINEERING PLASTIC KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-01-25 US claimed
US-5750715-A ELECTROGRAPHY WITH CHARGING EASTMAN KODAK COMPANY (US) 1998-05-12 US claimed
US-5723248-A Electrostatographic toners and developers containing bis 1,2-benzisthiazol-3(2h) -ylidene 1,1-dioxide) acetates!charge-control agents EASTMAN KODAK COMPANY (US) 1998-03-03 US claimed
US-5719000-A CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1998-02-17 US claimed
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed
EP-0123555-A2 Electrically photosensitive imaging materials EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-31 EP claimed
US-4473626-A Electrohardenable materials for photoelectrophoretic imaging EASTMAN KODAK COMPANY (US) 1984-09-25 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
EP-4716968-A1 BATTERY PACK COVER WITH A PROTRUDING DOUBLE WALL BATTERY DIVIDER AND THERMAL RUNAWAY BARRIER SABIC Global Technologies B.V. (NL) 2026-04-01 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4684445-A1 BATTERY PACK WITH BATTERY MODULE PARTIALLY SUBMERGED IN COOLANT SABIC Global Technologies B.V. (NL) 2026-01-28 EP disclosed
US-4013613-A INCLUDING ADDITION POLYMER GENERAL ELECTRIC COMPANY (US) 1977-03-22 US disclosed
US-4002581-A MOLDINGS GENERAL ELECTRIC COMPANY (US) 1977-01-11 US disclosed
US-3981841-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA TSHR 3048/4885CNR1 4611/4885CNR2 4530/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 TSHR 4263/4885CNR1 3103/4885CNR2 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.