SCHEMBL803437

SCHEMBL803437

CC(C)(C)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
POLB P06746 2/20 0.42
GAA P10253 2/20 0.41
CNR1 P21554 3/20 0.39
CNR2 P34972 3/20 0.39
ACLY P53396 1/20 0.39
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTR1D P28221 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.33
TYR P14679 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10183607 0.94 GABRA1 (0.52) TSHRGABRA1GABRB2POLBGAA
SCHEMBL25289427 0.84 GABRA1 (0.44) TSHRGABRA1GABRB2POLBGAA
SCHEMBL8826911 0.84 POLB (0.41) TSHRGABRA1GABRB2POLBGAA
SCHEMBL13249067 0.82 RAPGEF4 (0.44) TSHRGABRA1GABRB2POLBACLY
SCHEMBL9967852 0.82 GABRA1 (0.37) TSHRGABRA1GABRB2POLBGAA
SCHEMBL31465128 0.82 GABRA1 (0.37) TSHRGABRA1GABRB2POLBGAA
SCHEMBL16953294 0.82 GABRA1 (0.37) TSHRGABRA1GABRB2POLBGAA
SCHEMBL24019453 0.82 GABRA1 (0.37) TSHRGABRA1GABRB2POLBGAA
SCHEMBL20933032 0.82 GABRA1 (0.48) TSHRGABRA1GABRB2POLBGAA
SCHEMBL13208190 0.82 GABRA1 (0.37) TSHRGABRA1GABRB2POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007074-A1 LIGHT-EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT-EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-01 US disclosed
US-20260007073-A1 LIGHT-EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-01 US disclosed
US-20250338772-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 US disclosed
US-20250287842-A1 LIGHT EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-11 US disclosed
US-20250098539-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC DEVICE EACH INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2025-03-20 US disclosed
US-20240315135-A1 LIGHT EMITTING ELEMENT AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2024-09-19 US disclosed
CN-118530270-A Light-emitting element and condensed polycyclic compound for light-emitting element 三星显示有限公司 2024-08-23 CN disclosed
US-20240260291-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-08-01 US disclosed
US-20240239821-A1 N-ACYL FOSMIDOMYCIN PRODRUG ANALOGS AS NOVEL ANTIINFECTIVE AGENTS THE GEORGE WASHINGTON UNIVERSITY 2024-07-18 US disclosed
US-20240239821-A1 N-ACYL FOSMIDOMYCIN PRODRUG ANALOGS AS NOVEL ANTIINFECTIVE AGENTS THE GEORGE WASHINGTON UNIVERSITY 2024-07-18 US disclosed
US-20070066598-A1 Compounds BIOVITRUM AB, A SWEDEN CORPORATION 2007-03-22 US disclosed
US-20070037855-A1 Compounds for inhibiting beta-amyloid production and methods of identifying the compounds ALZHEIMER'S INSTITUTE OF AMERICA, INC. 2007-02-15 US disclosed
US-7176231-B2 Aryl-containing 5-acylindolinones, the preparation thereof and their use as medicaments BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-02-13 US disclosed
US-20070027321-A1 Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 MERCK SHARP & DOHME CORP. 2007-02-01 US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
US-20070015758-A1 Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors DR. REDDY'S LABORATORIES LTD. (IN) 2007-01-18 US disclosed
US-20070015758-A1 Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors DR. REDDY'S LABORATORIES LTD. (IN) 2007-01-18 US disclosed
US-20040082496-A1 ACE-2 modulating compounds and methods of use thereof MILLENNIUM PHARMACEUTICALS, INC. 2004-04-29 US disclosed
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-04-29 US disclosed
US-6512006-B1 Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties WARNER-LAMBERT COMPANY 2003-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082496-A1 ACE-2 modulating compounds and methods of use thereof ACE, ACE2, AGTR2 TSHR 2420/4885GABRA1 1098/4885GABRB2 454/4885
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ADORA2A, ADORA1, PDE2A TSHR 818/4885GABRA1 500/4885GABRB2 386/4885
US-20070066598-A1 Compounds SULT2A1, STS, SLC5A2 TSHR 1299/4885GABRA1 912/4885GABRB2 421/4885
US-20260007074-A1 LIGHT-EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT-EMITTING ELEMENT CCNL2, CRY1, CCNA1 TSHR 1977/4885GABRA1 3013/4885GABRB2 3212/4885
US-20240315135-A1 LIGHT EMITTING ELEMENT AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT NR2E3, LEF1, NFE2L2 TSHR 4114/4885GABRA1 1407/4885GABRB2 1515/4885
US-20260007073-A1 LIGHT-EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME NFE2L2, CCNL2, INF2 TSHR 3235/4885GABRA1 3681/4885GABRB2 3267/4885
US-20070037855-A1 Compounds for inhibiting beta-amyloid production and methods of identifying the compounds APP, PSEN1, PSEN2 TSHR 4253/4885GABRA1 1294/4885GABRB2 435/4885
US-20250287842-A1 LIGHT EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC DEVICE INCLUDING THE SAME NFE2L2, ELP1, LAGE3 TSHR 4355/4885GABRA1 2592/4885GABRB2 3076/4885
US-20070027321-A1 Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 GRM5, GRIK5, GRM1 TSHR 692/4885GABRA1 51/4885GABRB2 74/4885
US-20250338772-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT NR2E3, CRY1, LAGE3 TSHR 3181/4885GABRA1 753/4885GABRB2 1120/4885
US-20070015758-A1 Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors CETP, NPC1, DBI TSHR 3907/4885GABRA1 3300/4885GABRB2 2842/4885
US-20240239821-A1 N-ACYL FOSMIDOMYCIN PRODRUG ANALOGS AS NOVEL ANTIINFECTIVE AGENTS PSPH, PGLS, DNPEP TSHR 3740/4885GABRA1 3724/4885GABRB2 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.