Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579376 | 0.85 | RAPGEF4 (0.40) | TSHRPDE2ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL9152278 | 0.84 | PDE2A (0.38) | PDE2ARAPGEF4 | |
| Hydrochloric Acid SCHEMBL31410065 | 0.82 | PDE2A (0.36) | PDE2ARAPGEF4 | |
| SCHEMBL5184322 | 0.78 | PDE2A (0.42) | PDE2AGAAAKT1AKT2 | |
| SCHEMBL673309 | 0.77 | TSHR (0.50) | TSHRTP53CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL803437 | 0.77 | TSHR (0.50) | TSHRTP53CYP3A4CNR1CNR2 | |
| SCHEMBL9166484 | 0.76 | ALDH1A1 (0.41) | TSHRCYP3A4PDE2AAHRRAPGEF4 | |
| SCHEMBL1859294 | 0.75 | KIF11 (0.44) | TSHRCYP3A4PDE2AMEN1KMT2A | |
| SCHEMBL9602565 | 0.74 | TSHR (0.47) | TSHRTP53CYP3A4AHRCNR1 | |
| SCHEMBL9403849 | 0.74 | TSHR (0.47) | TSHRTP53CYP3A4AHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623529-B | Preparation method of oxaziclomefone | 山东先达农化股份有限公司 | 2021-11-26 | — | — | CN | claimed |
| US-20250100981-A1 | Cis-substituted 5-(hydroxymethyl)morpholine-2-carboxamides as agonists of SSTR4 | BOEHRINGER INGELHEIM INT (DE) | 2025-03-27 | — | — | US | disclosed |
| WO-2025027049-A1 | (2S,5R)-5-(HYDROXYMETHYL)MORPHOLINE-2-CARBOXAMIDES AS AGONISTS OF SSTR4 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |
| EP-4326257-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-116199701-A | Pyrazolooxazinone compound prepared based on intramolecular free radical cycloaddition and preparation method thereof | 安徽中医药大学 | 2023-06-02 | — | — | CN | disclosed |
| US-20220348568-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | INC., CHEMOCENTRYX | 2022-11-03 | — | — | US | disclosed |
| WO-2022225832-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| CN-108623529-B | Preparation method of oxaziclomefone | 山东先达农化股份有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-108623529-B | Preparation method of oxaziclomefone | 山东先达农化股份有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-104529789-B | Synthetic process of 3,5-dichloro-alpha,alpha-dimethyl benzylamine | 苏州市玮琪生物科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-0708597-A1 | HERBICIDAL COMPOSITIONS | RHONE-POULENC AGROCHIMIE (FR) | 1996-05-01 | — | — | EP | disclosed |
| US-5436224-A | Plant growth regulators | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0657099-A1 | Herbicidal composition | RHONE-POULENC AGROCHIMIE (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0372586-B1 | Cyclic amide compounds and herbicides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-5409886-A | For paddy rice fields | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-25 | — | — | US | disclosed |
| WO-1995002329-A1 | HERBICIDAL COMPOSITIONS | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-26 | — | — | WO | disclosed |
| EP-0605726-A1 | 1,3-OXAZIN-4-ONE DERIVATIVE, HERBICIDE CONTAINING THE SAME, AND NOVEL INTERMEDIATE FOR PRODUCING THE SAME | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5076834-A | 1,2,5,6-TETRAHYDROPYRIDINE-2-ONE COMPOUNDS WHICH ARE USEFUL HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-5006157-A | Pyrrolin-2-one compounds which are useful as herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0372586-A2 | Cyclic amide compounds and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348568-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | CXCR1, CXCR5, CXCR6 | TSHR 3385/4885TP53 3776/4885CYP3A4 2802/4885 |
| US-20250100981-A1 | Cis-substituted 5-(hydroxymethyl)morpholine-2-carboxamides as agonists of SSTR4 | SSTR4, SSTR5, SSTR2 | TSHR 38/4885TP53 4153/4885CYP3A4 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.