Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895994 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL29408467 | 0.82 | KMT2A (0.67) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL43644 | 0.82 | KMT2A (0.67) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL2427326 | 0.81 | KMT2A (0.53) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL21775802 | 0.81 | KMT2A (0.53) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL24572151 | 0.81 | KMT2A (0.53) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL7778033 | 0.80 | G6PD (0.60) | ALDH1A1HSD17B10GAAMAPTTSHR | |
| SCHEMBL7547221 | 0.80 | GAA (0.54) | ALDH1A1KMT2AGAAMAPTTSHR | |
| SCHEMBL31038441 | 0.80 | LMNA (0.66) | ALDH1A1HSD17B10CFTRKMT2AGAA | |
| SCHEMBL148358 | 0.80 | LMNA (0.66) | ALDH1A1HSD17B10CFTRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-6686106-B2 | POLYIMIDESILOXANE COPOLYMERS | UBE INDUSTRIES, LTD. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20020001763-A1 | Photosensitive resin compositions, insulating films, and processes for formation of the films | UBE INDUSTRIES, LTD. | 2002-01-03 | — | — | US | disclosed |
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |