Sugi Predict

Sugi Predict / Compounds / SCHEMBL148358

SCHEMBL148358

SCHEMBL148358

COC(=O)c1cccc(O)c1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.66
▸ TSHR P16473 1/20 0.66
▸ CASP7 P55210 2/20 0.60
▸ G6PD P11413 1/20 0.60
▸ CASP6 P55212 1/20 0.60
▸ CA1 P00915 4/20 0.59
▸ CA2 P00918 4/20 0.59
▸ CA9 Q16790 4/20 0.59
▸ CA12 O43570 3/20 0.59
▸ CA7 P43166 3/20 0.59
▸ CA14 Q9ULX7 3/20 0.59
▸ ALDH1A1 P00352 4/20 0.58
▸ HSD17B10 Q99714 2/20 0.58
▸ CFTR P13569 1/20 0.58
▸ GAA P10253 4/20 0.53
▸ CA5A P35218 1/20 0.51
▸ KDM4E B2RXH2 5/20 0.47
▸ ATM Q13315 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ PDK2 Q15119 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31038441 1.00 LMNA (0.66) LMNATSHRCASP7G6PDCASP6
SCHEMBL2895994 0.88 ALDH1A1 (0.67) LMNATSHRCASP7CA1CA2
Methyl Anthranilate SCHEMBL6251019 0.84 ALDH1A1 (0.68) LMNATSHRCASP7G6PDCASP6
SCHEMBL1004686 0.83 HSD17B10 (0.56) LMNATSHRCA1CA2CA9
SCHEMBL31589985 0.82 ALDH1A1 (0.71) LMNATSHRCASP7CA1CA2
SCHEMBL505249 0.82 ALDH1A1 (0.71) LMNATSHRCASP7CA1CA2
SCHEMBL27446077 0.81 G6PD (0.60) LMNATSHRCASP7G6PDCASP6
SCHEMBL14828745 0.81 ALDH1A1 (0.58) LMNATSHRCASP7CA1CA2
SCHEMBL228051 0.81 ALDH1A1 (0.58) LMNATSHRCASP7CA1CA2
SCHEMBL28957307 0.81 ALDH1A1 (0.58) LMNATSHRCASP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730657-B Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-07-12 — — CN claimed
CN-116730657-A Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-09-12 — — CN claimed
CN-107652248-A Synthesis method of anti-cancer drug UK-1 黄荣宗 2018-02-02 — — CN claimed
US-20160207909-A1 Synthesis Method of Anti-Cancer Drug UK-1 and Derivatives Thereof HUANG YUNG-TZUNG (TW) 2016-07-21 — — US claimed
US-7772009-B2 Room temperature phosphorescence apparatus and methods SCR Research, LLC (US) 2010-08-10 — — US claimed
US-20070117215-A1 Room temperature phosphorescence apparatus and methods POLYMER CONCEPTS TECHNOLOGIES PBY, INC. 2007-05-24 — — US claimed
JP-5247007-A — — None — — JP disclosed
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-07 — — US disclosed
US-12594277-B2 Macrocyclic ULK1/2 inhibitors SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-04-07 — — US disclosed
US-12410179-B2 Modulators of TNF alpha activity and uses thereof RAYTHERA, INC. (US) 2025-09-09 — — US disclosed
US-20250263418-A1 MODULATORS OF TNF ALPHA ACTIVITY AND USES THEREOF RAYTHERA, INC. 2025-08-21 — — US disclosed
US-20250179055-A1 Substituted 2-(pyrrolidine-3-yl)acetic acid derivative, preparation method and use thereof INNOVSTONE THERAPEUTICS LIMITED (CN) 2025-06-05 — — US disclosed
WO-2025103442-A1 SUBSTITUTED 2-(PYRROLIDIN-3-YL)ACETIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2025-05-22 — — WO disclosed
WO-1998016503-A2 THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1998-04-23 — — WO disclosed
EP-0820441-A1 INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-01-28 — — EP disclosed
EP-0749415-A1 BENZAMIDE ANALOGS, USEFUL AS PARP (ADP-RIBOSYLTRANSFERASE, ADPRT) DNA REPAIR ENZYME INHIBITORS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 1996-12-27 — — EP disclosed
WO-1996032379-A1 INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-10-17 — — WO disclosed
WO-1995024379-A1 BENZAMIDE ANALOGS, USEFUL AS PARP (ADP-RIBOSYLTRANSFERASE, ADPRT) DNA REPAIR ENZYME INHIBITORS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 1995-09-14 — — WO disclosed
JP-H05247007-A NEW BENZOXAZOLE COMPOUND SUNTORY LTD 1993-09-24 — — JP disclosed
US-4110246-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410179-B2 Modulators of TNF alpha activity and uses thereof TNF, TNFRSF1A, TNFRSF9 LMNA 2008/4885TSHR 2273/4885CASP7 528/4885
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS ZC3HAV1, CCR1, CCR6 LMNA 1783/4885TSHR 2194/4885CASP7 1472/4885
US-12594277-B2 Macrocyclic ULK1/2 inhibitors ULK1, ULK2, ULK3 LMNA 3488/4885TSHR 3103/4885CASP7 1826/4885
US-20160207909-A1 Synthesis Method of Anti-Cancer Drug UK-1 and Derivatives Thereof ALDH7A1, ADH1A, ALDH1A1 LMNA 3929/4885TSHR 4243/4885CASP7 836/4885
US-20250179055-A1 Substituted 2-(pyrrolidine-3-yl)acetic acid derivative, preparation method and use thereof PCSK9, LPL, LYPLA1 LMNA 81/4885TSHR 3539/4885CASP7 1263/4885
US-20250263418-A1 MODULATORS OF TNF ALPHA ACTIVITY AND USES THEREOF TNF, TNFRSF1A, TNFRSF9 LMNA 2008/4885TSHR 2273/4885CASP7 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.