SCHEMBL6735826

SCHEMBL6735826

OCc1cc(F)c(CO)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
ACLY P53396 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RECQL P46063 1/20 0.32
TAAR1 Q96RJ0 2/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522619 0.84 ACHE (0.43) ACHENPC1RAB9AHPGDSMN1; SMN2
SCHEMBL523766 0.84 ACHE (0.43) ACHETAAR1CYP4F2CYP4A11KIF11
SCHEMBL15545063 0.80 CNR1 (0.35) TAAR1
SCHEMBL17414237 0.80 ALDH1A1 (0.39) HPGDSMN1; SMN2RECQLTAAR1
SCHEMBL15814084 0.80 ACHE (0.37) ACHEACLYNPC1RAB9AHPGD
SCHEMBL17414230 0.80 ACHE (0.37) ACHEACLYNPC1RAB9AHPGD
SCHEMBL29738548 0.80 ACHE (0.37) ACHEACLYNPC1RAB9AHPGD
SCHEMBL4681948 0.78 TAAR1 (0.48) ACHENPC1RAB9AHPGDSMN1; SMN2
SCHEMBL23287117 0.77 NMT1 (0.32) ACLYRECQLTAAR1
SCHEMBL15545176 0.77 L3MBTL1 (0.33) ACLYNPC1RAB9ASMN1; SMN2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1226258-C Process for producing fluorinated methyl-benzyl alcohol SHOWAN DENKO K K (JP) 2005-11-09 CN disclosed
US-6828467-B2 Industrial process of the hydrogenolysis of one hydroxyl or methanol group of a fluorinated benzenedimethanol carried out in a solvent in the presence of a catalyst; 2,3,5,6-tetra-fluorobenzyl alcohol from the 4-methyl derivative SHOWA DENKO K.K. (JP) 2004-12-07 US disclosed
EP-1322584-B1 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO KK (JP) 2004-11-24 EP disclosed
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol SHOWA DENKO K.K. (JP) 2004-01-15 US disclosed
CN-1466560-A Process for producing fluorinated methyl-benzyl alcohol �Ѻ͵繤��ʽ���� 2004-01-07 CN disclosed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP disclosed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol ADH1C, ADH5, ADH1A ACHE 2586/4885ACLY 4764/4885NPC1 2185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.