Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | HRH2 | P25021 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027153 | 0.85 | CCR3 (0.48) | HRH1HRH2ALDH1A1CCR3NAMPT | |
| SCHEMBL6741934 | 0.82 | KDM1A (0.38) | HRH1HRH2NAMPTDRD3HTR1A | |
| SCHEMBL7482983 | 0.81 | ALDH1A1 (0.37) | HRH1HRH2ALDH1A1DRD3HTR1A | |
| SCHEMBL7106389 | 0.78 | HRH2 (0.47) | HRH1HRH2 | |
| SCHEMBL6999554 | 0.77 | HRH2 (0.48) | HRH1HRH2ALDH1A1 | |
| SCHEMBL7030216 | 0.74 | KCNH2 (0.51) | HRH1HRH2ALDH1A1 | |
| SCHEMBL7032117 | 0.73 | CYP11B2 (0.38) | HRH1HRH2MAOBKDM1ACNR2 | |
| SCHEMBL7482979 | 0.73 | HRH1 (0.35) | HRH1HRH2ALDH1A1CCR3NAMPT | |
| SCHEMBL6996460 | 0.72 | HTR1A (0.41) | HRH1HRH2ALDH1A1DRD3HTR1A | |
| SCHEMBL6743201 | 0.72 | NAMPT (0.44) | HRH1HRH2CCR3NAMPTDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ADRA1B, ADRB2, ADRA1D | HRH1 184/4885HRH2 113/4885MAOA 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.