SCHEMBL674014

SCHEMBL674014

CCc1cc(C)c(C)c(-c2c(-c3cc(CC)cc(C)c3C)c(-c3cc(CC)cc(C)c3C)c3c(c2-c2cc(CC)cc(C)c2C)=c2ccccc2=3)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27740148 0.81 NPC1 (0.37) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL1882864 0.75 NPC1 (0.36) NPC1ALDH1A1RAB9AL3MBTL1
SCHEMBL27747973 0.72 PTGS1 (0.41) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL1883337 0.72 SKP2 (0.41) NPC1MAPK1RAB9ACYP1A2
SCHEMBL27747977 0.71 CD274 (0.40) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL9723265 0.71 ALDH1A1 (0.47) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL599609 0.69 RAPGEF4 (0.41) NPC1ALDH1A1MAPTMAPK1RAB9A
SCHEMBL1893689 0.68 HSP90AA1 (0.32) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL674648 0.67 TDP2 (0.39) NPC1ALDH1A1MAPK1RAB9ASMN1; SMN2
SCHEMBL9723282 0.66 ELANE (0.39) NPC1LMNAMAPTMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117642466-A Polyphenylene ether resin composition and molded article 菱环球聚甲醛株式会社 2024-03-01 CN disclosed
WO-2022255015-A1 POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE 三菱エンジニアリングプラスチックス株式会社 2022-12-08 WO disclosed
EP-2617772-B1 POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE OF SAME MITSUBISHI ENG PLASTICS CORP (JP) 2020-02-12 EP disclosed
EP-2604643-B1 THIN-WALL ARTICLE MITSUBISHI GAS CHEMICAL CO (JP) 2018-05-30 EP disclosed
EP-2792714-B9 MOLDED PRODUCTS MITSUBISHI GAS CHEMICAL CO (JP) 2018-04-04 EP disclosed
EP-2570459-B1 POLYAMIDE RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2018-02-21 EP disclosed
EP-2792714-B1 MOLDED PRODUCTS MITSUBISHI GAS CHEMICAL CO (JP) 2017-08-23 EP disclosed
EP-2586813-B1 REACTIVE POLYAMIDE RESIN AND POLYAMIDE RESIN COMPOSITIONS MITSUBISHI GAS CHEMICAL CO (JP) 2017-04-05 EP disclosed
EP-1995280-B1 FLAME RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDING MITSUBISHI ENG PLASTICS CORP (JP) 2016-08-24 EP disclosed
EP-2644637-B1 POLYAMIDE RESIN AND METHOD FOR MOLDING SAME MITSUBISHI GAS CHEMICAL CO (JP) 2015-10-07 EP disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-1925640-B1 RESIN COMPOSITIONS AND RESIN MOLDINGS MITSUBISHI CHEM CORP (JP) 2010-08-11 EP disclosed
US-20090326110-A1 RESIN COMPOSITION AND RESIN MOLDED PRODUCT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2009-12-31 US disclosed
US-20090309073-A1 THERMOPLASTIC RESIN COMPOSITION FOR PRODUCING AUTOMOBILE EXTERIOR PARTS DSM IP ASSETS B.V. (NL) 2009-12-17 US disclosed
US-20090312468-A1 FLAME RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2009-12-17 US disclosed
EP-2028230-A1 THERMOPLASTIC RESIN COMPOSITION FOR PRODUCING AUTOMOBILE EXTERIOR PART Mitsubishi Engineering-Plastics Corporation (JP) 2009-02-25 EP disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
EP-1995280-A1 FLAME RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDING Mitsubishi Engineering-Plastics Corporation (JP) 2008-11-26 EP disclosed
EP-1925640-A1 RESIN COMPOSITIONS AND RESIN MOLDINGS Mitsubishi Chemical Corporation (JP) 2008-05-28 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed