Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740971 | 0.87 | CYP3A4 (0.54) | CYP3A4LMNACYP1A2TSHRCYP2C9 | |
| SCHEMBL28033051 | 0.80 | LMNA (0.58) | CYP3A4LMNACYP1A2TSHRCYP2C9 | |
| SCHEMBL6082056 | 0.78 | TSHR (0.56) | CYP3A4LMNACYP1A2TSHRCYP2C9 | |
| SCHEMBL29042899 | 0.77 | TSHR (0.54) | CYP3A4LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL8537398 | 0.77 | PTGIR (0.43) | LMNATSHRALDH1A1MAPTGAA | |
| SCHEMBL9228232 | 0.77 | LMNA (0.55) | CYP3A4LMNACYP1A2TSHRCYP2C9 | |
| SCHEMBL3661310 | 0.75 | KEAP1 (0.49) | LMNATSHRALDH1A1NPC1MAPT | |
| SCHEMBL17377345 | 0.74 | GAA (0.39) | LMNATSHRALDH1A1NPC1MAPT | |
| SCHEMBL16682336 | 0.73 | LMNA (0.54) | CYP3A4LMNACYP1A2TSHRCYP2C9 | |
| SCHEMBL14975876 | 0.73 | TSHR (0.50) | CYP3A4LMNACYP1A2TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1322598-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028820-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | NQO2, SULT1A1, NAT1 | CYP3A4 1241/4885LMNA 1575/4885CYP1A2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.