Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927967 | 0.81 | CES2 (0.41) | PTGIRPTGDRTSHRCES2CES1 | |
| SCHEMBL29042899 | 0.78 | TSHR (0.54) | PTGIRPTGDRTSHRLMNATP53 | |
| SCHEMBL6740204 | 0.77 | CYP3A4 (0.52) | PTGIRPTGDRTSHRLMNATDP1 | |
| SCHEMBL6548684 | 0.76 | NOS3 (0.55) | CES2CES1ALDH1A1MAPTMEN1 | |
| SCHEMBL6740971 | 0.73 | CYP3A4 (0.54) | PTGIRPTGDRTSHRLMNATP53 | |
| SCHEMBL29233093 | 0.72 | LMNA (0.55) | PTGIRPTGDRTSHRLMNATP53 | |
| SCHEMBL19505630 | 0.70 | ESR1 (0.60) | CES2CES1ALDH1A1MAPTMEN1 | |
| SCHEMBL17017261 | 0.70 | ESR2 (0.66) | CES2CES1 | |
| SCHEMBL3661310 | 0.70 | KEAP1 (0.49) | TSHRLMNATP53KDM4EHPGD | |
| SCHEMBL10689367 | 0.69 | LTB4R2 (0.54) | PTGIRPTGDRTSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028290-A1 | SYNTHESIS OF OLIGOARYLAMINES, AND USES AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-06-10 | — | — | WO | disclosed |