SCHEMBL6740328

SCHEMBL6740328

Cc1ccc(N)c(OCCO)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
MAPT P10636 4/20 0.47
L3MBTL1 Q9Y468 4/20 0.47
HSD17B10 Q99714 3/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 2/20 0.47
MAPK1 P28482 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 4/20 0.43
CYP3A4 P08684 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALOX15 P16050 2/20 0.43
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.43
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
CYP2C9 P11712 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20214357 0.88 TDP1 (0.50) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL3094604 0.85 ALDH1A1 (0.55) ALDH1A1MAPTHSD17B10MEN1POLB
SCHEMBL1341908 0.83 ALDH1A1 (0.53) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL23568201 0.82 ALDH1A1 (0.62) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL9596753 0.82 L3MBTL1 (0.51) ALDH1A1MAPTL3MBTL1HPGDMEN1
SCHEMBL11956988 0.81 L3MBTL1 (0.47) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL12280900 0.81 ALDH1A1 (0.55) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL1342454 0.81 CYP1A2 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10HPGD
SCHEMBL516010 0.81 TSHR (0.64) ALDH1A1L3MBTL1HPGDMEN1POLB
SCHEMBL29393081 0.81 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384302-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11384302-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11359151-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-06-14 US disclosed
CN-113440418-A Dental polymerizable composition 株式会社GC 2021-09-28 CN disclosed
WO-2020260417-A1 METHODS FOR PREPARING BENZOXAZINES BP OIL INTERNATIONAL LIMITED (GB) 2020-12-30 WO disclosed
WO-2020260418-A1 METHODS FOR PREPARING BENZOXAZINES BP OIL INTERNATIONAL LIMITED (GB) 2020-12-30 WO disclosed
CN-112041306-A Method for producing a fuel additive 英国石油国际有限公司 2020-12-04 CN disclosed
EP-3732173-A1 METHODS FOR PREPARING FUEL ADDITIVES BP Oil International Limited (GB) 2020-11-04 EP disclosed
US-20200332211-A1 Methods for Preparing Fuel Additives BP OIL INTERNATIONAL LIMITED (GB) 2020-10-22 US disclosed
US-20200332210-A1 Methods for Preparing Fuel Additives BP OIL INTERNATIONAL LIMITED (GB) 2020-10-22 US disclosed
US-20200332210-A1 Methods for Preparing Fuel Additives BP OIL INTERNATIONAL LIMITED (GB) 2020-10-22 US disclosed
US-10251827-B2 Oxidation dyeing process using a composition comprising a monoaminobenzene and a metal catalyst L'OREAL (FR) 2019-04-09 US disclosed
US-20160128922-A1 OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST L'OREAL (FR) 2016-05-12 US disclosed
US-20160128922-A1 OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST L'OREAL (FR) 2016-05-12 US disclosed
WO-2014202787-A1 OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST L'OREAL (FR) 2014-12-24 WO disclosed
US-6685751-B2 SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES WELLA AKTIENGESELLSCHAFT (DE) 2004-02-03 US disclosed
US-20030110578-A1 Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200332210-A1 Methods for Preparing Fuel Additives GSDMD, DEGS1, SCD ALDH1A1 1552/4885MAPT 3033/4885L3MBTL1 4251/4885
US-10251827-B2 Oxidation dyeing process using a composition comprising a monoaminobenzene and a metal catalyst KRT18, CYB5R3, CBR3 ALDH1A1 444/4885MAPT 1029/4885L3MBTL1 4003/4885
US-20200332211-A1 Methods for Preparing Fuel Additives GSDMD, SCD, FADS1 ALDH1A1 1572/4885MAPT 3161/4885L3MBTL1 4274/4885
US-11359151-B2 Methods for preparing fuel additives GSDMD, SCD, FADS1 ALDH1A1 1572/4885MAPT 3161/4885L3MBTL1 4274/4885
US-20160128922-A1 OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST KRT18, CYB5R3, CBR3 ALDH1A1 441/4885MAPT 863/4885L3MBTL1 4036/4885
US-20030110578-A1 Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same KRT18, AOC1, DAO ALDH1A1 43/4885MAPT 2345/4885L3MBTL1 4677/4885
US-11384302-B2 Methods for preparing fuel additives GSDMD, DEGS1, SCD ALDH1A1 1552/4885MAPT 3033/4885L3MBTL1 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.