Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1528331 | 0.73 | KDM4E (1.00) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL18284865 | 0.67 | HSD17B10 (0.53) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL2493952 | 0.66 | KDM4E (0.58) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5792174 | 0.66 | ALPL (0.67) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5789379 | 0.66 | KDM4E (1.00) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5028318 | 0.65 | ACHE (0.59) | TSHRPOLBHSD17B10ALDH1A1GAA | |
| SCHEMBL8894861 | 0.64 | MEN1 (0.54) | KDM4EPOLBHSD17B10ALDH1A1GAA | |
| SCHEMBL5924532 | 0.64 | KDM4E (0.62) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL9084539 | 0.63 | ADORA3 (0.40) | ALDH1A1ACHECRHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8706033 | 0.63 | ACHE (0.56) | TSHRPOLBHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | disclosed |
| EP-0984960-B1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI SYNTHELABO (FR) | 2003-02-05 | — | — | EP | disclosed |
| EP-0984960-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998051686-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | KDM4E 1971/4885TSHR 197/4885POLB 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.