Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD1 | P21728 | 5/20 | 0.40 |
| ▸ | DRD5 | P21918 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256371 | 0.83 | SLC6A3 (0.47) | OPRD1OPRM1OPRK1SLC6A4 | |
| SCHEMBL18856220 | 0.77 | DRD2 (0.47) | OPRD1DRD2DRD1DRD5DRD3 | |
| SCHEMBL6306629 | 0.76 | CRHBP (0.38) | DRD3OPRM1 | |
| SCHEMBL11256289 | 0.72 | OPRD1 (0.71) | OPRD1OPRM1OPRK1SLC22A1CHRM2 | |
| SCHEMBL6306922 | 0.72 | HTR5A (0.68) | HTR5AMCL1DRD2DRD3 | |
| SCHEMBL6743192 | 0.70 | OPRM1 (0.39) | OPRD1OPRM1OPRK1SLC6A4 | |
| SCHEMBL7816263 | 0.70 | CYP1A2 (0.57) | HTR5AMCL1DRD2SLC6A4CYP2D6 | |
| SCHEMBL7951002 | 0.70 | DRD2 (0.41) | OPRD1DRD2DRD3DRD4 | |
| SCHEMBL4824477 | 0.69 | OPRL1 (0.41) | OPRD1OPRM1OPRK1ACHE | |
| SCHEMBL23921740 | 0.69 | HRH3 (0.40) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767782-B1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER (US) | 2001-10-31 | — | — | EP | disclosed |
| CN-1064350-C | Aryl and heteroaryl alkoxynaphtalene derivatives | PFIZER (US) | 2001-04-11 | — | — | CN | disclosed |
| US-6166020-A | Aryl and heteroaryl alkoxynaphthalene derivatives | PFIZER INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-5821245-A | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | disclosed |
| CN-1151729-A | Aryl and heteroaryl alkoxynaphtalene derivatives | PFIZER (US) | 1997-06-11 | — | — | CN | disclosed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | disclosed |