Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746020 | 0.86 | DHODH (0.39) | DHODHSCN9AGALR1 | |
| SCHEMBL6747092 | 0.83 | KIF11 (0.33) | KIF11PTGS2PTGS1 | |
| SCHEMBL6746687 | 0.83 | PTGS2 (0.39) | KIF11PTGS2PTGS1FFAR4SCN5A | |
| SCHEMBL6746478 | 0.83 | PTGS2 (0.43) | KIF11PTGS2 | |
| SCHEMBL6743712 | 0.82 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL6744935 | 0.82 | PTGS2 (0.36) | KIF11PTGS2PTGS1 | |
| SCHEMBL6746753 | 0.81 | PTGS2 (0.45) | KIF11PTGS2PTGS1 | |
| SCHEMBL6744681 | 0.81 | PTGS2 (0.40) | KIF11PTGS2PTGS1ABL1BCR | |
| SCHEMBL6746439 | 0.80 | CASP1 (0.39) | KIF11PTGS2PTGS1 | |
| SCHEMBL6745120 | 0.79 | ACLY (0.35) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |