Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747092 | 0.91 | KIF11 (0.33) | PTGS2PTGS1GRM2KIF11BRD4 | |
| SCHEMBL6743255 | 0.83 | KIF11 (0.44) | PTGS2SCN5AFFAR4PTGS1KIF11 | |
| SCHEMBL6743877 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1KIF11 | |
| SCHEMBL6747309 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6745350 | 0.82 | PTGS2 (0.41) | PTGS2SCN5AFFAR1FFAR4PTGS1 | |
| SCHEMBL6746358 | 0.82 | KIF11 (0.46) | PTGS2PTGS1KIF11 | |
| SCHEMBL6746730 | 0.81 | PTGS2 (0.38) | PTGS2KIF11 | |
| SCHEMBL6746020 | 0.80 | DHODH (0.39) | — | |
| SCHEMBL6749827 | 0.80 | KIF11 (0.43) | PTGS2PTGS1KIF11 | |
| SCHEMBL6746746 | 0.79 | PTGS2 (0.35) | PTGS2PTGS1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |